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UID:6083@i2m.univ-amu.fr
DTSTART;TZID=Europe/Paris:20220413T140000
DTEND;TZID=Europe/Paris:20220413T150000
DTSTAMP:20241120T200909Z
URL:https://www.i2m.univ-amu.fr/evenements/modelling-locomotor-dynamics-in
 -drosophila-larvae/
SUMMARY:Barbara WEBB (University of Edinburgh\, UK): Modelling locomotor dy
 namics in Drosophila larvae
DESCRIPTION:Barbara WEBB: The Drosophila larva is an important model system
  for understanding the interaction of neural circuits and body mechanics i
 n directed locomotion. Its behaviour is often described as alternating bet
 ween straight peristaltic crawling (runs) produced by a central pattern ge
 nerator (CPG)\, and lateral bending to reorient (turns)\, either for rando
 m exploration or to move up or down a sensory gradient (taxis) by making a
 ppropriate ‘decisions’ when to switch. To better understand the contro
 l of motion we have developed a mathematical model of larval segmental mec
 hanics\, and show that (in the absence of damping and driving) the mechani
 cs of the body produce axial travelling waves\, lateral oscillations\, and
  unpredictable\, chaotic deformations. Adding a simple reflexive neuromusc
 ular circuit to this model to counter friction gives rise to forward and b
 ackward peristalsis and turning\, even though the nervous system has no CP
 G and neither senses nor drives bending motions. This produces life-like e
 xploratory behaviour\, and by adding a reflex to enhance bending in respon
 se to sensory input\, we can produce directed taxis that closely resembles
  the observed behaviour of larvae in a sensory gradient.\nIOSSB Seminar
ATTACH;FMTTYPE=image/jpeg:https://www.i2m.univ-amu.fr/wp-content/uploads/2
 022/01/Barbara_Webb.jpg
CATEGORIES:Interdisciplinary online seminar series on
 Biolocomotion,Virtual event
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