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UID:6985@i2m.univ-amu.fr
DTSTART;TZID=Europe/Paris:20190710T140000
DTEND;TZID=Europe/Paris:20190710T153000
DTSTAMP:20241209T194949Z
URL:https://www.i2m.univ-amu.fr/evenements/propagation-de-fronts-et-croiss
 ance-tumorale-hdr-guillemette-chapuisat/
SUMMARY:Guillemette Chapuisat (I2M\, Aix-Marseille Université): Propagatio
 n de fronts et croissance tumorale (HDR Guillemette Chapuisat)
DESCRIPTION:Guillemette Chapuisat: https://tel.archives-ouvertes.fr/tel-029
 61114\n\nProgressive fronts and cancer growth\nThis work deals with the an
 alysis of reaction-diffusion equations and modeling in health science. In 
 a first part\, we are interested in understanding the propagation or not o
 f depolarization wave in the brain. This problem arises from the modeling 
 of cortical spreading depressions and amounts to studying the influence of
  the geometry of the domain on the propagation of a generalized transition
  front for a bistable reaction-diffusion equation. Sliding methods are use
 d to prove the propagation of a front and energy methods to construct stat
 ionary solutions blocking the front. Finally\, a numerical study of an ope
 n case is presented. The second part of this work concerns the modeling in
  cancerology and more precisely the study and the optimization of the chem
 otherapy protocols to fight cancer. In particular\, the “Maximum Tolerat
 ed Dose” protocols in which a high dose of chemotherapy followed by a lo
 ng pause is periodically given\, is compared with the metronomic protocols
  in which lower but more frequent doses are given\, using different models
 . Finally\, optimal control tools are used to obtain new protocols.\n\nMem
 bres du jury :\n- Henri BERESTYCKI (EHESS)\n- Emmanuel GRENIER (ENS Lyon)\
 n- François HAMEL (Aix-Marseille Université)\n- Raphaèle HERBIN (Aix-Ma
 rseille Université)\n- Florence HUBERT (Aix-Marseille Université)\n- Él
 isabeth LOGAK (Université de Cergy-Pontoise)\n- Hasnaa ZIDANI (ENSTA Pari
 s)\n\nLien :\n- ResearchGate
ATTACH;FMTTYPE=image/jpeg:https://www.i2m.univ-amu.fr/wp-content/uploads/2
 020/01/Guillemette_Chapuisat.jpg
CATEGORIES:Soutenance d'HdR,Analyse Appliquée
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DTSTART:20190331T030000
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