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UID:5477@i2m.univ-amu.fr
DTSTART;TZID=Europe/Paris:20100331T110000
DTEND;TZID=Europe/Paris:20100331T120000
DTSTAMP:20241028T212752Z
URL:https://www.i2m.univ-amu.fr/evenements/top-down-phylogenetic-tree-reco
 nstruction-celine-vens/
SUMMARY:Celine Vens (KULAK\, a KU Leuven campus in Kortrijk\, Belgium): Top
 -down phylogenetic tree reconstruction - Celine Vens
DESCRIPTION:Celine Vens: We propose a novel distance based method for recon
 struction of phylogenetic trees. Our method is based on a conceptual clust
 ering method that extends the decision tree learning approach. Our method 
 starts from a single cluster and repeatedly splits it into subclusters unt
 il all sequences form a different cluster. We assume that a split can be d
 escribed by referring to particular polymorphic locations\, which makes su
 ch a divisive method computationally feasible.\nTo define the best split\,
  our method uses a criterion that is close to Neighbor Joining's (NJ) opti
 mization criterion\, namely\, constructing a phylogenetic tree with minima
 l total branch length. Our approach has a number of important advantages.\
 nFirst\, by listing the polymorphic locations at the internal nodes\, it p
 rovides an explanation for the resulting tree topology.\nSecond\, the resu
 lting trees can be used as classification trees to add new sequences to th
 e phylogeny.\nThird\, the top-down tree growing process can be stopped bef
 ore a complete tree is generated\, yielding an efficient gene or protein s
 ubfamily identification approach.\nOur algorithm\, called Clus-I+\, can be
  found at http://www.cs.kuleuven.be/~dtai/clus.\n\n&nbsp\;
ATTACH;FMTTYPE=image/jpeg:https://www.i2m.univ-amu.fr/wp-content/uploads/2
 020/01/Celine_Vens.jpg
CATEGORIES:Séminaire,Mathématiques-Évolution-Biologie
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DTSTART:20100328T030000
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