Adaptation from standing genetic variation

Possible analytical approaches:

• Hermisson/Pennings with moving optimum (selection gradient increases linearly); use results from Uecker and Hermisson 2011?
• Hermisson/Pennings for quantitative trait (functional relationship between selection coefficients before and after environmental change; ask which mutation from sgv is most likely to fix first)
• use bi-allelic infinite sites model without linkage as a simple extension of one-locus case
• Concentrate on HC-regime (relatively low mutation rate, distribution of new mutations independent of parent allele; predominant wild-type allele)
• Potentially useful papers: Keightly and Hill 1988, Foley 1982)

Simulations:

• Study simple cases (one-locus; two-allele infinite sites)
• make comparisons: sudden vs. gradual change; new mutations vs. sgv