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standing_genetic_variation [2013/06/13 10:45] – created mkoppstanding_genetic_variation [2019/03/21 09:21] (current) – external edit 127.0.0.1
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 ====== Adaptation from standing genetic variation ====== ====== Adaptation from standing genetic variation ======
  
 +Possible analytical approaches:
 +  * Hermisson/Pennings with moving optimum (selection gradient increases linearly); use results from Uecker and Hermisson 2011?
 +  * Hermisson/Pennings for quantitative trait (functional relationship between selection coefficients before and after environmental change; ask which mutation from sgv is most likely to fix first)
 +  * use bi-allelic infinite sites model without linkage as a simple extension of one-locus case
 +  * Concentrate on HC-regime (relatively low mutation rate, distribution of new mutations independent of parent allele; predominant wild-type allele)
 +  * Potentially useful papers: Keightly and Hill 1988, Foley 1982)
  
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 +Simulations:
 +  * Study simple cases (one-locus; two-allele infinite sites)
 +  * make comparisons: sudden vs. gradual change; new mutations vs. sgv